American Uranium (ASX:AMU) made one point clear at yesterday’s RIU Uranium Investment Day, Lo Herma is moving out of pure exploration mode.
The Wyoming ISR project now hosts 9.96Mlb of uranium at an average grade of 630ppm, with 7.38Mlb already sitting inside the three mine units currently being assessed for development. Around 54% of that development footprint is classified as Indicated.
That resource base is now feeding directly into hydrogeological work, leach testing and a Scoping Study targeted for the fourth quarter of 2026.
The question is starting to shift from how much uranium is there to how Lo Herma could actually be developed.
The ISR case is getting firmer
The technical work to date supports alkaline in-situ recovery, while a large-scale aquifer pump test has now been completed with results pending.
That matters because Lo Herma is not being treated as a conventional uranium mine.
The development concept is built around ISR, where uranium is recovered through wellfields rather than a traditional open pit or underground operation.
American Uranium is concentrating technical work across Mine Units 1, 2 and 3, using the data to assess wellfield design, leach characteristics, process options and early capital inputs.

Figure 1: Lo Herma Project and proposed mine units.
Wyoming does some of the heavy lifting
Lo Herma also benefits from where it sits.
The project is located in Wyoming’s Powder River Basin, around 10 miles from Cameco’s Smith Ranch operation and inside a broader corridor of established ISR infrastructure.
That gives American Uranium options.
A standalone central processing plant remains one pathway, but the company is also evaluating whether existing licensed infrastructure could support a lower-capex satellite model.
No processing or tolling access has been secured, but the surrounding infrastructure means the development conversation starts from a more advanced position than a greenfield project in an isolated basin.

Figure 2: Powder river basin.
The US uranium gap keeps getting harder to ignore
The timing is doing no harm either.
The US produced only 2.2Mlb of uranium in 2025, while 92.3% of uranium purchased by US nuclear operators in 2024 was foreign-origin.
That puts domestic projects like Lo Herma into a much broader strategic conversation around nuclear fuel security.
American Uranium is pitching Lo Herma as one of the few independently controlled, defined ISR development assets in Wyoming, with the scale now beginning to compare with other projects in the state.

Figure 3: New nuclear power capacity added by year.

Figure 4: Where the US buys its nuclear fuel – U3O8 – Country of origin.
What comes next
The immediate program is straightforward.
Complete the pump-test interpretation. Finish the Scoping Study. Continue the water monitoring and mine-unit technical work.
Then AMU has to decide which development pathway makes the most sense.
American Uranium’s 2026-27 program is explicitly aimed at taking Lo Herma to that strategic decision point.
The exploration story has already found uranium, the next phase is about working out the quickest and most economic way to get it out.
View the full presentation here.



